Research

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• Imbalance between circulating CD4(+) regulatory T and conventional T lymphocytes in patients with HBV-related acute-on-chronic liver failure.
• Prognostic factors in acute-on-chronic liver failure: A prospective study from western India.
• Effect of a carbohydrate-containing late-evening snack on energy metabolism and fasting substrate utilization in adults with acute-on-chronic liver failure due to Hepatitis B.
• Risk factors for invasive pulmonary aspergillosis and hospital mortality in acute-on-chronic liver failure patients: a retrospective-cohort study.
• Impacts of pretransplant infections on clinical outcomes of patients with acute-on-chronic liver failure who received living-donor liver transplantation.
• APACHE II score is superior to SOFA, CTP and MELD in predicting the short-term mortality in patients with acute-on-chronic liver failure (ACLF).
• Hepatic and systemic hemodynamic derangements predict early mortality and recovery in patients with acute-on-chronic liver failure.
• Liver transplantation in acute-on-chronic liver failure patients with high model for end-stage liver disease (MELD) scores: a single center experience of 100 consecutive cases.
• Amelioration of liver injury by continuously targeted intervention against TNFRp55 in rats with acute-on-chronic liver failure.
• Restoring the Treg cell to Th17 cell ratio may alleviate HBV-related acute-on-chronic liver failure.
• Blockade of high-mobility group box-1 ameliorates acute on chronic liver failure in rats.
• Invasive fungal infections secondary to acute-on-chronic liver failure: a retrospective study.
• Experience of combined liver-kidney transplantation for acute-on-chronic liver failure patients with renal dysfunction.
• High level of IL-27 positively correlated with Th17 cells may indicate liver injury in patients infected with HBV.
• A modified MELD model for Chinese pre-ACLF and ACLF patients and it reveals poor prognosis in pre-ACLF patients.
• Distinct quasispecies characteristics and positive selection within precore/core gene in hepatitis B virus HBV associated acute-on-chronic liver failure.
• Relation between serum levels of high mobility group box 1 and hepatitis B virus-related acute-on-chronic liver failure.[Article in Chinese]
• The efficacy and safety of nucleos(t)ide analogues in the treatment of HBV-related acute-on-chronic liver failure: a meta-analysis.
• Short-term entecavir versus lamivudine therapy for HBeAg-negative patients with acute-on-chronic hepatitis B liver failure.
• Association of a single-nucleotide polymorphism within the miR-146a gene with susceptibility for acute-on-chronic hepatitis B liver failure.
• Association of Toll-like receptor 3 polymorphisms with chronic hepatitis B and hepatitis B-related acute-on-chronic liver failure.
• Hepatic coagulopathy-intricacies and challenges; a cross-sectional descriptive study of 110 patients from a superspecialty institute in North India with review of literature.
• KCTD9 contributes to liver injury through NK cell activation during hepatitis B virus-induced acute-on-chronic liver failure.
• Etiology, clinical profile, and inhospital mortality of acute-on-chronic liver failure: a prospective study.
• Imbalance of interleukin-17-producing CD4 T cells/regulatory T cells axis occurs in remission stage of patients with hepatitis B virus-related acute-on-chronic liver failure.
• Granulocyte-colony stimulating factor therapy improves survival in patients with hepatitis B virus-associated acute-on-chronic liver failure.
• CD34+ hematopoietic stem cells mobilization, paralleled with multiple cytokines elevated in patients with HBV-related acute-on-chronic liver failure.
• Effects of xenogeneic adipose-derived stem cell transplantation on acute-on-chronic liver failure.
• Intrahepatic expression of programmed death-1 and its ligands in patients with HBV-related acute-on-chronic liver failure.
• Comparison of long-term outcome of patients with Wilson's disease presenting with acute liver failure versus acute-on-chronic liver failure.
• Increased Th17 cells and interleukin-17 contribute to immune activation and disease aggravation in patients with chronic hepatitis B virus infection.
• Artificial liver support system combined with liver transplantation in the treatment of patients with acute-on-chronic liver failure.
• Distribution of traditional Chinese medicine patterns in 324 cases with hepatitis B-related acute-on-chronic liver failure: a prospective, cross-sectional survey.
• High mobility group box chromosomal protein 1 in acute-on-chronic liver failure patients and mice with ConA-induced acute liver injury.
• The characteristic expression of B7-H3 and B7-H4 in liver biopsies from patients with HBV-related acute-on-chronic liver failure.
• Human mesenchymal stem cell transfusion is safe and improves liver function in acute-on-chronic liver failure patients.
• Hepatic stellate cells are involved in the pathogenesis of acute-on-chronic liver failure (ACLF).
• Predictors of the outcomes of acute-on-chronic hepatitis B liver failure.
• Phenotypes and clinical significance of circulating CD4(+)CD25(+) regulatory T cells (Tregs) in patients with acute-on-chronic liver failure (ACLF).
• What MELD score mandates use of entecavir for ACLF-HBV HBeAg-negative patients?
• Improved survival ratios correlate with myeloid dendritic cell restoration in acute-on-chronic liver failure patients receiving methylprednisolone therapy.
• Nucleoside analogues improve the short-term and long-term prognosis of patients with hepatitis B virus-related acute-on-chronic liver failure.
• Augmenter of liver regeneration may be a candidate for prognosis of HBV related acute-on-chronic liver failure as a regenerative marker.
• Analysis of the relationship between hepatitis B virus precore and basal core promoter mutations and acute-on-chronic liver failure.[Article in Chinese]
• Enhanced peripheral γδT cells cytotoxicity potential in patients with HBV-associated acute-on-chronic liver failure might contribute to the disease progression.
• Severe acute exacerbation of chronic hepatitis B during pegylated interferon treatment and early intervention with corticosteroid.
• Comparison of four prognostic models and a new Logistic regression model to predict short-term prognosis of acute-on-chronic hepatitis B liver failure.
• Dynamics of serum HBV DNA levels during the terminal phases of acute-on-chronic hepatitis B liver failure with different HBeAg status.[Article in Chinese]
• Efficacy of lamivudine on acute-on-chronic liver failure in patients with chronic hepatitis B.[Article in Chinese]
• Different models in predicting the short-term prognosis of patients with hepatitis B virus-related acute-on-chronic liver failure.
• Psychological comorbidities in Chinese patients with acute-on-chronic liver failure.
• Expression of CD39 on FoxP3+ T regulatory cells correlates with progression of HBV infection.
• Acute-on-chronic liver failure in chronic hepatitis B.
• Dissection of a circulating and intrahepatic CD4(+)Foxp3(+) T-cell subpopulation in chronic hepatitis B virus (HBV) infection: a highly informative strategy for distinguishing chronic HBV infection states.
• Clinical profile and predictors of mortality in patients of acute-on-chronic liver failure.
• Monitoring oxidative stress in acute-on-chronic liver failure by advanced oxidation protein products.
• Immunopathogenesis and prognostic immune markers of chronic hepatitis B virus infection.
• Noninvasive measurement of liver fibrosis by transient elastography and influencing factors in patients with chronic hepatitis B-A single center retrospective study of 466 patients.
• Association of a TANK gene polymorphism with outcomes of hepatitis B virus infection in a Chinese Han population.
• A prospective cohort study on the influence of high doses of herbs for clearing heat and resolving stasis on survival rates in patients with hepatitis B-related acute-on-chronic liver failure.[Article in Chinese]
• The relationship of HBeAg status with HBV DNA loads, MELD scores in patients with acute-on-chronic hepatitis B liver failure during terminal phases.[Article in Chinese]
• Survival analysis of short-term prognosis of patients with HBV-related acute-on-chronic liver failure.[Article in Chinese]
• Pre-core/basal-core promoter and reverse transcriptase mutations in chronic HBV infected-patients
• Acute on chronic liver disease in children from the developing world: recognition and prognosis.
• Prevalence and clinical significance of Cryptosporidium infection in patients with hepatitis B virus-associated acute-on-chronic liver failure.
• Discussion on the meaning of MELD score in the opportunity of the entecavir treatment of HBeAg-negative acute-on-chronic liver failure. [Article in Chinese
• Survival and prognostic factors in hepatitis B virus-related acute-on-chronic liver failure.
• The ratio of Th-17 to Treg cells is associated with survival of patients with acute-on-chronic hepatitis B liver failure.
• Liver histology as predictor of outcome in patients with acute-on-chronic liver failure (ACLF).
• Interleukin-21 is upregulated in hepatitis B-related acute-on-chronic liver failure and associated with severity of liver disease.
• Circulating microRNAs in hepatitis B virus-infected patients.
• Expression of COX-2 and PPARg in the livers of patients with acute on chronic HBV-related liver failure and their relationship with clinic parameters. [Article in Chinese]
• Predictors of outcome in acute-on-chronic liver failure in children.
• T1846 and A/G1913 are associated with acute on chronic liver failure in patients infected with hepatitis B virus genotypes B and C.
• Protective effects of ACLF sera on metabolic functions and proliferation of hepatocytes co-cultured with bone marrow MSCs in vitro.
• Comparison of MELD-Na versus MELDNa in the prediction of short-term prognosis for acute-on-chronic hepatitis B liver failure. [Article in Chinese]
• Resting energy expenditure and substrate metabolism in patients with acute-on-chronic hepatitis B liver failure.
• The analysis of IL-10 and its methylation in the patients with acute on chronic liver failure. [Article in Chinese]
• Tenofovir improves the outcome in patients with spontaneous reactivation of hepatitis B presenting as acute-on-chronic liver failure.
• Association of hepatitis B virus mutations in basal core promoter and precore regions with severity of liver disease: an investigation of 793 Chinese patients with mild and severe chronic hepatitis B and acute-on-chronic live
• Efficacy of short-term dexamethasone therapy in acute-on-chronic pre-liver failure.
• Hepatitis B virus genotype and basal core promoter/precore mutations are associated with hepatitis B-related acute-on-chronic liver failure without pre-existing liver cirrhosis.
• Skewed ratios between CD3(+) T cells and monocytes are associated with poor prognosis in patients with HBV-related acute-on-chronic liver failure.
• Non-hepatic insults are common acute precipitants in patients with acute on chronic liver failure (ACLF).
• A retrospective study of clinical and pathological spectrum in 91 patients with chronic severe hepatitis B. [Article in Chinese]
• Nucleoside analogue can improve the long-term prognosis of patients with hepatitis B virus infection-associated acute on chronic liver failure.
• Persistent effect of IFNAR-1 genetic polymorphism on the long-term pathogenesis of chronic HBV infection.
• Lamivudine and entecavir significantly improved the prognosis of early-to-mid stage hepatitis B related acute on chronic liver failure. [Article in Chinese]
• Analysis the relationship of HBV BCP A1762T/G1764A double mutation with HBV related acute on chronic liver failure. [Article in Chinese]
• Research of PD-1 expression in CD8+ T cell of peripheral blood with HBV-associated acute-on-chronic liver failure. [Article in Chinese]
• Influential factors of prognosis in lamivudine treatment for patients with acute-on-chronic hepatitis B liver failure.
• Serum peptide profiles during progression of chronic hepatitis B virus infection to liver failure.
• Serum thymosin beta4 levels in patients with hepatitis B virus-related liver failure.
• Interleukin-17-producing CD4(+) T cells increase with severity of liver damage in patients with chronic hepatitis B.
• Increased killing of liver NK cells by Fas/Fas ligand and NKG2D/NKG2D ligand contributes to hepatocyte necrosis in virus-induced liver failure.
• Compartmentalization and its implication for peripheral immunologically-competent cells to the liver in patients with HBV-related acute-on-chronic liver failure.
• Prediction of the prognosis of patients with acute-on-chronic hepatitis B liver failure using the model for end-stage liver disease scoring system and a novel logistic regression model.
• Mammillary body atrophy in acute liver failure and acute-on-chronic liver failure of nonalcoholic etiology.
• Hemodynamic studies in acute-on-chronic liver failure.
• Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific Association for the study of the liver (APASL).
• Clinical features and predictors of outcome in acute hepatitis A and hepatitis E virus hepatitis on cirrhosis.
• Hepatitis E virus is a leading cause of acute-on-chronic liver disease: experience from a tertiary centre in Bangladesh.
• Imbalanced intrahepatic cytokine expression of interferon-gamma, tumor necrosis factor-alpha, and interleukin-10 in patients with acute-on-chronic liver failure associated with hepatitis B virus infection.
• Role of cytokines in the pathophysiology of acute-on-chronic liver failure.
• In vivo 1H magnetic resonance spectroscopy-derived metabolite variations between acute-on-chronic liver failure and acute liver failure.
• Prediction value of model for end-stage liver disease scoring system on prognosis in patients with acute-on-chronic hepatitis B liver failure after plasma exchange and lamivudine treatment.
• Quantification of cerebral edema on diffusion tensor imaging in acute-on-chronic liver failure.
• Evaluation of mannitol effect in patients with acute hepatic failure and acute-on-chronic liver failure using conventional MRI, diffusion tensor imaging and in-vivo proton MR spectroscopy.
• A comparison of rabbit mesenchymal stem cells and anterior cruciate ligament fibroblasts responses on combined silk scaffolds.
• Altered immune function of monocytes in different stages of patients with acute on chronic liver failure.
• Functional assessment of elderly subjects in four service settings.
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